Vascular Permeability/Vascular Endothelial Growth Factors: A Potential Role in the Pathogenesis and Treatment of Vascular Diseases
نویسندگان
چکیده
منابع مشابه
role of vascular endothelial growth factors in ocular neovascular diseases
the most important progress in the field of retinal diseases during recent years might be the introduction of pharmacotherapy. age-related macular degeneration for instance was an irreversible disease leading to permanent anatomical and functional changes in the macula up to the previous decade; however, the use of anti-vascular endothelial growth factor agents (anti-vegfs) not only stops the p...
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Vascular endothelial growth factors (VEGFs) are key regulators of permeability. The principal evidence behind how they increase vascular permeability in vivo and in vitro and the consequences of that increase are addressed here. Detailed analysis of the published literature has shown that in vivo and in vitro VEGF-mediated permeability differs in its time course, but has common involvement of m...
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OBJECTIVES/HYPOTHESIS Vascular endothelial growth factor (VEGF) is a critical mediator of vascular permeability and angiogenesis and likely plays an important role in cochlear function and hearing. This review highlights the role of VEGF in hearing loss associated with vestibular schwannomas, otitis media with effusion, and sensorineural hearing loss. STUDY DESIGN PubMed literature review. ...
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Coronary heart diseases are the most preventable non-contagious diseases, but unfortunately, ‎it is one of the major causes of mortality among humans in the industrialized and semi-‎industrialized countries. It is predicted that if this trend continues, it will lead to the death of ‎approximately over ‎‏25‏‎ million people in the world by ‎‏2020‏‎. On...
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Hypoxia is known to be a major factor in the induction of angiogenesis during tumor development but its role in lymphangiogenesis remains unclear. Blood and lymphatic vasculatures are stimulated by the vascular endothelial family of growth factors - the VEGFs. In this review, we investigate the role of hypoxia in the molecular regulation of synthesis of the lymphangiogenic growth factors VEGF-A...
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ژورنال
عنوان ژورنال: Vascular Medicine
سال: 1996
ISSN: 1358-863X,1477-0377
DOI: 10.1177/1358863x9600100403